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O3–11–03: Arterial stiffness is associated with amyloid deposition in the brain independent of blood pressure
Author(s) -
Kuller Lewis,
Hughes Timothy,
BarinasMitchell Emma,
Mackey Rachel,
McDade Eric,
Klunk William E.,
Mathis Chester,
DeKosky Steven,
Snitz Beth,
Price Julie,
Ikonomovic Milos,
Lopez Oscar
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.04.299
Subject(s) - pulse wave velocity , cardiology , arterial stiffness , medicine , blood pressure , hyperintensity , pulse pressure , cerebral blood flow , magnetic resonance imaging , radiology
Association between age and diffusion properties for different white matter tractsICV indicates intra cranial volume, WML white matter lesion, FA fractional anisotropy, MD mean diffusivity, ATR anterior thalamic radiation, IFO inferior fronto-occipital fasciculus, ILF inferior longitudinal fasciculus, PTR posterior thalamic radiation, SLF superior longitudinal fasciculus, UNC uncinate fasciculus, FMA forceps major, FMI forceps minor, CGC cingulate gyrus part of cingulum, CGH parahippocampal part of cingulum, CST corticospinal tract, MCP middle cerebellar peduncle, ML medial lemniscus, STR superior thalamic radiation.Values represent normalized regression coefficients for change in FA or MD per year increase in age, adjusted for sex and ICV (and additionally for tract volume and WML load in other models). Significant associations (at Bonferroni corrected threshold p1⁄40.0004) are printed in bold Tracts are ordered by functional role.