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P2‐281: The scale of delayed story recall: A brief screening tool for amnestic mild cognitive impairment in Chinese elderly
Author(s) -
Tian Jinzhou,
Shi Jing,
Wei Mingqing,
Miao Yingchun,
Wang Yongyan
Publication year - 2012
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2012.05.989
Subject(s) - cutoff , receiver operating characteristic , recall , dementia , audiology , wechsler adult intelligence scale , cognitive impairment , psychology , cognition , medicine , psychiatry , disease , cognitive psychology , physics , quantum mechanics
was to validate the HVLT Chinese version and develop proper cut-off point in detecting mild cognitive impairment (MCI) or Alzheimer’s disease (AD) from population with normal cognition (NC).Methods:A t otal of 631 subjects aged 60 and over were recruited in a Memory Clinic at Dongzhimen Hospital in Beijing. Of them, 249 subjects were considered as NC, 134 were considered as MCI, 97 subjects were considered as AD, 1 4 subjects met the diagnosis of vascular dementia (VaD), 50 subjects were considered as other dementia including mixed dementia. Discriminative capacity of the HVLT total recall, recognition score and total scores were calculated by the sensitivity and specificity of these tests for detecting MCI or AD and other dementia for various cut scores. Results: The score of the HVLT was impacted by age, education and sex. The HVLT total recall showed an optimal balance between sensitivity and specificity using a cut-off score of 15.5 for detecting AD or other dementia from NC using the ROC curve, with the same sensitivity 94.7% for detecting AD and other dementia, and specificity 92.5% for AD, 93.4% for other dementia. When the cutoff score was 21.5 in the HVLT total recall, an optimal balance were obtained between the sensitivity (69.1%) and specificity (70.7%) in detecting MCI from NC. The HVLT were highly correlated to the Mini-mental state examination (MMSE) (r 1⁄4 0.856,P 1⁄4 0.000). Conclusions: The cut-off score 15.5 of the HVLT total recall score was showed a good discriminative capacity between dementia and normal controls. This data suggests that the HVLT total recall score can be used as brief tool in discriminating well dementia but not MCI from NC in clinical and epidemiological practice.