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P2‐091: The impact of oxidative stress upon membrane fluidity and cytoplasmic lipids peroxidation in red blood cells from hypertensive patients of different ages with stroke
Author(s) -
Revnic Cristian,
Revnic Floarea
Publication year - 2012
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2012.05.795
Subject(s) - catalase , lipid peroxidation , oxidative stress , antioxidant , glutathione peroxidase , medicine , membrane fluidity , red blood cell , stroke (engine) , superoxide dismutase , chemistry , endocrinology , biochemistry , membrane lipids , dismutase , membrane , mechanical engineering , engineering
tumoral K526 cells in the presence or absence of inducer Results: Our data have pointed out that the quantity of p nitoaniline liberated following enzyme activity was almost to 1⁄2 in patients with stroke suggesting a decreased level of Casp3 activity. A correlation has been made between basal proloferative capacity of lymphocyte and caspase 3 activity in stroke patients; the increase in basal proliferative capacity of lymphocytes is accompanied by a reduction in casp.3 activity in stroke patients, while in controls proliferative capacity of lymphocytes is decreased and apoptosis intensity is increased.Conclusions: We can conclude that anti-inflamatory potential is strongly expressed in cardiovascular pathology while the apoptosis intensity is reduced.