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P1‐232: Chronic BACE inhibition halts further age‐related increases in brain Aß and amyloid plaques in aged TgCRND8 mice with established plaques
Author(s) -
Hyde Lynn,
Cantu Cinzia,
Werner Bonnie,
Chen Xia,
Sondey Marie,
Chen Maxine,
Weig Blair,
LaShomb Abigail,
Lu Sherry,
Hodgson Robert,
Scott Jack,
Cumming Jared,
Stamford Andrew,
Parker Eric,
Kennedy Matthew
Publication year - 2012
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2012.05.511
Subject(s) - amyloid precursor protein secretase , amyloid precursor protein , morris water navigation task , pharmacology , prepulse inhibition , chemistry , amyloid (mycology) , cognitive decline , genetically modified mouse , alzheimer's disease , endocrinology , medicine , pathology , neuroscience , transgene , biochemistry , disease , hippocampus , dementia , psychology , schizophrenia (object oriented programming) , psychiatry , gene

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