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P1‐088: Investigation of the factor relevant to cognitive activity routinely in Japanese older adults
Author(s) -
Ihira Hikaru,
Furuna Taketo,
Sato Shinichi,
Gondo Yasuyuki,
Hirano Hirohiko,
Watanabe Shuichiro
Publication year - 2012
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2012.05.364
Subject(s) - logistic regression , odds ratio , cognition , confidence interval , gerontology , medicine , stepwise regression , demography , psychology , psychiatry , sociology
ity complications), and macrovascular complications (cardiovascular disease, stroke). Results: 17.29% (5,074) were diagnosed with dementia. Age-adjusted dementia incidence rates were highest amongNAs and blacks, lowest among Asians (Table). After adjustment for sex and education, dementia risk remained higher among NAs and blacks, lower among Asians, and similar among Latinos (relative to NHW) (Table). Further adjustment for T2DM severity and control as well as T2DM-related complications (microvascular or macrovascular) did not substantively alter hazard ratios for dementia (Table). Conclusions: Among older T2DM patients with uniform access to care, dementia risk was moderately higher among NAs and blacks, lower among Asians, and similar among Latinos, compared to NHW. These differences were robust to T2DM-related microvascular or macrovascular complications nor markers of T2DM severity and control. Among T2DM patients, blacks and NAs represent groupsmore susceptible to dementia. Racial/ethnic differences were not explained by a wide range of potential mediators.