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P2‐397: Neuroprotective efficacy of ANAVEX2‐73, a novel tetrahydrofuran derivative targeting the sigma‐1 chaperone protein, in a mouse model of Alzheimer's disease: Analyses of administration schedules and combination studies with donepezil
Author(s) -
Maurice Tangui,
Vamvakides Alexandre
Publication year - 2012
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2012.05.1107
Subject(s) - neuroprotection , pharmacology , spontaneous alternation , chemistry , amyloid beta , donepezil , neurotoxicity , oxidative stress , toxicity , medicine , endocrinology , peptide , biochemistry , hippocampal formation , dementia , disease
1. C6H5 60% 172-174 C17H12N4SO 320.38 1693 (C1⁄4O) 164 (C-2), 173 (C-4), 17.4 (CA) 2. p-OCH3C6H4 60% 185-187 C18H14N4SO2 350.4