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P2‐359: Cathepsin B gene deletion or inhibition improves memory deficits in a mouse model of Alzheimer's disease expressing APP with the wild‐type beta‐secretase site
Author(s) -
Hook Greg,
Yu Jin,
Zhu Hong,
ElAmouri Salim,
Hook Vivian,
Kindy Mark
Publication year - 2012
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2012.05.1069
Subject(s) - cathepsin b , biology , amyloid precursor protein , cathepsin d , cathepsin , genetically modified mouse , gene knockout , microbiology and biotechnology , amyloid beta , alzheimer's disease , amyloid precursor protein secretase , proteases , presenilin , transgene , gene , biochemistry , enzyme , medicine , peptide , pathology , disease
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