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P2‐077: Smell identification test as a progression marker in Alzheimer's disease
Author(s) -
Velayudhan Latha,
Pritchard Megan,
Lovestone Simon
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.967
Subject(s) - olfaction , cognition , dementia , audiology , memory clinic , psychology , disease , mini–mental state examination , alzheimer's disease , cognitive decline , medicine , test (biology) , clinical psychology , psychiatry , neuroscience , paleontology , biology
Factors influencing or predicting progression in Alzheimer's disease (AD) is not well understood. Olfactory dysfunction, impaired smell identification in particular, is known to occur in AD. Mesial temporal lobe, important for memory function is also critical for the processing of olfactory information. In view of a common anatomical substrate, we hypothesized that olfaction dysfunction worsens faster in people with AD with rapid cognitive decline compared to those with slower cognitive decline.