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P1‐457: Heading disorientation in young‐onset Alzheimer's disease patients
Author(s) -
Pai MingChyi
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.739
Subject(s) - heading (navigation) , retrosplenial cortex , orientation (vector space) , audiology , psychology , disease , perception , developmental psychology , medicine , physical medicine and rehabilitation , neuroscience , cortex (anatomy) , geometry , mathematics , geodesy , geography
(3 a-MCI and 1 md-MCI) result anosognosic, while other four subjects over-estimated their defects, on the basis of AQ-D. Moreover, 32 patients exhibited behavioral abnormalities, irritability (N1⁄413), apathy and anxiety (N1⁄4 11) being the most frequent. Irritability and apathy were also the items causing the higher burden for care-givers. Apathy was more frequent in naMCI patients, if comparing the three groups. No correlations were found between anosognosia and NPI scores.Conclusions: These results suggest that the diagnosis of anosognosia is infrequent and that the awareness of cognitive functions is extremely variable in patients with MCI, ranging from low knowledge to exaggeration of symptoms. Furthermore, neuropsychiatric symptoms are common features of MCI.