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P1‐444: Brief screening for mild cognitive impairment: initial validation of the Montreal cognitive assessment (MoCA) in Brazilian elderly
Author(s) -
Memória Cláudia,
Bertolucci Paulo,
Sarmento Ana Luisa,
Wajman José Roberto,
Forlenza Orestes
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.726
Subject(s) - montreal cognitive assessment , receiver operating characteristic , cronbach's alpha , intraclass correlation , prodrome , medicine , cognition , cognitive impairment , gerontology , psychology , clinical psychology , psychiatry , psychometrics , psychosis
were analyzed. Results: A 3 (group) x 2 (trial) analysis of variance (ANOVA), with repeated measures on the last factor, was conducted on the semantic clustering scores. The significant main effects of group [F(2,138)1⁄431.06, p < 0.01] and trial [F(1, 138)1⁄454.76, p < 0.01] were modified by a significant interaction [F(2, 138)1⁄416.60, p < 0.01]; clustering increased from learning to the long delay in healthy controls [t(52)1⁄4 8.00, p < 0.01] and to a lesser degree in MCI [t(55)1⁄43.54, p < 0.01], but not inAD [t(31)1⁄41.54, p> 0.05]. For the recall data, a similar analysis found significant main effects of group [F(2,138)1⁄488.47, p < 0.01] and trial [F(1, 138)1⁄4196.34, p< 0.01] that were modified by a significant interaction [F(2, 138)1⁄412.13, p < 0.01]; still, all three groups showed better trial 5 performance than delayed free recall (all t’s > 6.13, all p’s < 0.01). Conclusions: These results indicate that healthy controls exhibit increased strategy use even after information is already learned. Individuals with MCI show this increase in strategy use, but to a lesser degree, while persons with AD show no change in clustering. These findings were not mirrored by the recall data, in which all groups showed declines in performance from the last learning trial to delayed free recall. Our findings suggest that changes in strategy use are reflective of early cognitive difficulties in MCI.