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P1‐416: Individual differences in cognitive plasticity and variability as predictors of cognitive function in older adults
Author(s) -
Grand Jacob,
MacDonald Stuart,
Hultsch David
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.697
Subject(s) - cognition , psychology , multilevel model , episodic memory , cognitive decline , effects of sleep deprivation on cognitive performance , cognitive skill , verbal memory , developmental psychology , dementia , medicine , neuroscience , disease , pathology , machine learning , computer science
similar magnitude. In AD, HV was most strongly associated with ADNIMem. Conclusions: Our memory composite score detected rates of change better than other candidate summary scores. It was the strongest predictor of conversion fromMCI to AD. ADNI-Mem was one of the measures best predicted by the CSF measures in MCI, and by Aß in AD. For MRI, ADNIMemwas competitivewith the ADAS-Cog. ADNI-Memmay serve as a better benchmark for sample size comparisons.