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O1‐01‐03: Meta‐Analysis of Rare CLU Variants Shows Association with Alzheimer's Risk and Calls Attention To The CLU Beta‐Subunit
Author(s) -
Bettens Karolien,
Brouwers Nathalie,
Engelborghs Sebastiaan,
Lambert JeanCharles,
Vandenberghe Rik,
Pasquier Florence,
De Deyn Peter,
Amouyel Philippe,
Van Broeckhoven Christine,
Sleegers Kristel
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.2435
Subject(s) - clusterin , missense mutation , cohort , genetics , allele , biology , genome wide association study , genetic association , oncology , medicine , bioinformatics , gene , mutation , genotype , single nucleotide polymorphism , apoptosis
St ephanie Debette, Helena Schmidt, James Wilson, Velandai Srikanth, Lina Zgaga, Mirna Kirin, Lei Yu, Jim Stankovich, Qiong Yang, Reinhold Schmidt, Caroline Hayward, Harry Campbell, Jan Bressler, Gail Davies, Josh Bis, Katja Petrovic, David Bennett, Sudha Seshadri, Albert Smith, Carla Ibrahim-Verbaas, Thomas Mosley, Mohammad Ikram, Maaike Schuur, Cornelia van Duijn, Monique Breteler, Ian Deary, Lenore Launer, Annette Fitzpatrick, Department of Neurology, Boston University School of Medicine, Boston, USA; 2 Department of Neurology, Medical University of Graz; Centre for Population Health Sciences, University of Edinburgh, Edinburgh; Stroke and Ageing Research Group, Neurosciences, Dept of Medicine, Southern Clinical School, Clayton, Victoria; 5 Public Health Sciences, University of Edinburgh, Edinburgh; 6 Centre for Population Health Sciences, University of Edinburgh, Edinburgh; Rush Alzheimer’s Disease Center, Rush University Medical Center, chicago, Illinois; The Menzies Research Institute, Hobart, Australia; 9 Boston University School of Medicine, Boston, Massachusetts; 10 Department of Neurology, Medical University of Graz, Graz; Public Health Sciences, University of Edinburgh, Edinburgh, United Kingdom; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom; 13 Human Genetics Center RAS E-503, Houston, Texas; Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom; Department of Medicine, University of Washington, Seattle, Washington; 16 Department of Neurology, Medical University of Graz; 17 Department of Neurology, Boston University School of Medicine, the Framingham Heart Study, Boston, Massachusetts; AGES Reykjavik Icelandic Heart Association, Kopavogur, Iceland; 19 Erasmus University Medical Center, Rotterdam, The Netherlands; 20 Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi; Erasmus University Medical Center, Rotterdam, the Netherlands; Erasmus University Medical Center, Rotterdam; 23 Dept of Epidemiology, Erasmus MC, University Medical Center, Rotterdam; University of Edinburgh; Intramural Research Program, National Institute on Aging, Bethesda, Maryland; University of Washington, Seattle, Washington.