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P4‐274: Towards a model of sporadic Alzheimer's disease: Aiding design of small molecule TrkA agonists
Author(s) -
Watson Judy,
Shoemark Deborah,
Hemmings Jennifer,
Tyler Susan,
Fahey Mark,
Williams Christopher,
Bailey Christopher,
McArdle Craig,
Caunt Christopher,
Jane David,
Sessions Richard,
Crump Matthew,
Willis Christine,
Allen Shelley
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.2310
Subject(s) - tropomyosin receptor kinase a , low affinity nerve growth factor receptor , nerve growth factor , neurotrophin , trk receptor , microbiology and biotechnology , basal forebrain , cholinergic , chemistry , cholinergic neuron , mapk/erk pathway , receptor , biology , neuroscience , signal transduction , biochemistry
It appears that Alzheimer’s disease is a good deal more complete than previously thought and may well have multiple dimensions than just Amyloid Cascade Hypothesis as the only culprit causing the disease. DR. Kokjohn spoke about a more holistic approach taken in the research, where multiple factors are taken into effect in the cause of Alzheimer’s. Tyler explained the difference between Alzheimer’s & Dementia.