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O4‐02‐02: TXNIP, the major player in insulin resistance, is early over‐expressed in the brain of the 5XFAD Alzheimer's mice model and is induced by Aβ in vitro: Emerging role of TXNIP and inflammation in Alzheimer's Disease progression
Author(s) -
Gouget Tiphany,
Djelloul Mehdi,
Boucraut Jose,
Weinhard Laetitia,
Baranger Kevin,
Rivera Santiago,
Khrestchatisky Michel,
Perrone Lorena
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.1973
Subject(s) - txnip , insulin resistance , medicine , diabetes mellitus , vascular dementia , microglia , dementia , alzheimer's disease , endocrinology , disease , inflammation , biology , oxidative stress , thioredoxin
RESISTANCE, IS EARLY OVER-EXPRESSED IN THE BRAIN OF THE 5XFAD ALZHEIMER’S MICE MODEL AND IS INDUCED BYAb IN VITRO: EMERGING ROLE OF TXNIP AND INFLAMMATION IN ALZHEIMER’S DISEASE PROGRESSION Tiphany Gouget, Mehdi Djelloul, Jose Boucraut, Laetitia Weinhard, KevinBaranger, SantiagoRivera,MichelKhrestchatisky,LorenaPerrone, 1 Neurobiologie des interactions cellulaires et neurophysiopathologie (NICN), Marseille, France; CNRS UMR 6231, Marseille, France; UMR 6184 CNRS-Universit e de la M editerran ee, Marseille, France.