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P3‐293: Androgen intervention therapy in a patient with familial Alzheimer's disease
Author(s) -
Martins Ralph,
Gupta Veer Bala,
Sohrabi Hamid,
Clarnette Roger,
Zentner Adrian,
Paton Athena,
Taddei Kevin,
Lenzo Nat,
Salvado Olivier,
Morris John
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.1735
Subject(s) - clusterin , medicine , testosterone (patch) , biomarker , apolipoprotein e , amyloid (mycology) , endocrinology , oncology , gastroenterology , disease , pathology , biology , apoptosis , biochemistry
associated withWBA, although this association was not observed in the ML direction. Conclusions: Our findings indicate that the rate of whole brain atrophy is related to trunk movement control during dual-task gait, but not normal gait. This supports the idea that dual-task gait is more cognitively demanding than normal gait. In addition, it suggests that trunk movement control recruits neuronal resources. Additional studies are necessary to further elucidate the effects of regional atrophy on the control of gait.