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P3‐248: Trends in the prevalence of dementia in Japan: a preliminary report
Author(s) -
Ikejima Chiaki,
Hisanaga Akito,
Ymada Tatsuo,
Nakajima Kenji,
Yamada Shigeto,
Kakuma Tatsuyuki,
Mizukami Katsuyoshi,
Asada Takash
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.1689
Subject(s) - dementia , medicine , neuropsychology , population , psychiatry , life expectancy , dementia with lewy bodies , frontotemporal dementia , disease , gerontology , pediatrics , family medicine , cognition , pathology , environmental health
Background: In Japan, life expectancy is now higher than in any other country, and the graying of society has been proceeding with remarkable speed. The proportion of the population over the age of 65 reached 23% in 2009. Therefore, we investigated the prevalence and illnesses causing dementia and the use of social services to perceive issues facing Japanese communities. Methods: 4 catchment areas were chosen for the target, and a 3,208 elderly sample was selected based upon census data from October 1, 2009. A door-to-door, three-phase survey was carried out in each area. The ascertainment of cases was made between November 2009 and September 2010. The study included a psychiatric interview; physical, neurologic, and neuropsychological examinations; comprehensive laboratory tests, and cranial computed tomography. Dementia was defined according to theDiagnostic and Statistical Manual of Mental Disorders, fourth edition, National Institute of Neurological Communicative Disorders and Stroke-Alzheimer’s Disease and Related Disorders Association, National Institute of Neurologic Disorders and Stroke-Association Internationale pour la Recherche et l’Enseignement en Neurosciences. Revised criteria for the clinical diagnosis of dementia with Lewy bodies, Lund-Manchester diagnostic criteria for frontotemporal dementia. In addition, mild cognitive impairment (MCI) was defined according to criteria of the “Japanese Alzheimer’s disease neuroimaging initiative”. This study was approved by the ethics committee of University of Tsukuba. Results: The participant rate for each area was 52.5 79.2%, and 2,187 participants were examined. The prevalence of dementia was 12.4 15.7%, and MCI was 11.1 19.9%. Of the illnesses causing dementia, Alzheimer’s disease was the most frequent (67.6%), followed by vascular dementia (18.7%), dementia with Lewy body disease (4.5%), mixed dementia (4.2%), and other illnesses. Conclusions: The prevalence of dementia in this study was higher than previous reports in Japan and other countries. To investigate the upward trend of dementia prevalence and its background factors, we have scheduled another 3 catchment area survey in 2011-2012. The present study was supported in part by a research grant from the Ministry of Health, Labor and Welfare.