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P2‐506: Efficacy and safety of systemic versus intracerebroventricular delivery of a β‐secretase (BACE1) small molecule inhibitor in a mouse model of Alzheimer's disease
Author(s) -
Thakker Deepak,
Sankaranarayanan Sethu,
Weatherspoon Marcy,
Harrison Jonathan,
Pierdomenico Maria,
Heisel Jennifer,
Nix Bradley,
Thompson Lorin,
Haskell Roy,
Grace James,
Taylor Sarah,
Albright Charles,
Stewart Gregory,
Shafer Lisa
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.1377
Subject(s) - systemic administration , in vivo , pharmacology , medicine , ex vivo , drug delivery , toxicity , amyloid precursor protein secretase , drug , pharmacokinetics , amyloid precursor protein , alzheimer's disease , chemistry , disease , biology , microbiology and biotechnology , organic chemistry
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