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P2‐188: Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women
Author(s) -
Blackwell Terri,
Stone Katie,
AncoliIsrael Sonia,
Ensrud Kristine,
Cauley Jane,
Redline Susan,
Hillier Teresa,
Yaffe Kristine
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.1074
Subject(s) - dementia , medicine , circadian rhythm , prospective cohort study , cohort , actigraphy , cohort study , odds ratio , quartile , confidence interval , physical therapy , gerontology , disease
tients, prevalence rate: 3.7%), 5.1% an AD with depressive mood and 14.9% a mixed AD. Prevalence rate of ADWAwas 4.8% and 3.5% among the patients included respectively by psychiatrists or GPs(p 1⁄4 0.13). The main life stressor events involved in ADWA development were: serious personal illness or health problem (29.4%), illness of a familymember (20.6%), familial conflict (12.5%), problems with children (as child leaving the family, divorce.)(7.4%), and work-related problems (7.4%). On Sheehan disability scale, at least moderate discomfort was observed in 82% of patients and a severe discomfort in 48.2%. Conclusions: The ADWA is frequent in aged patients with a prevalence rate of 3.7%. This underlines the importance of the phenomenology and suggests to study the link between anxiety and possible occurrence of dementia.