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P2‐124: Sex hormones and TNF‐alpha in men with Alzheimer's disease
Author(s) -
Birch Brian,
Butchart Joe,
Wolfe Laura,
Holmes Clive
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.1012
Subject(s) - sex hormone binding globulin , medicine , testosterone (patch) , hormone , endocrinology , luteinizing hormone , population , cohort , androgen , physiology , environmental health
cluding 76 unaffected controls. All received retrospective ratings of premorbid personality. Results: Highly significant correlation between abnormal personality factors (solitary, anxious, dependent) and the prevalence of AD. Rates of personality disorder in the same nursing home population of 9.3%, and this featured a significantly larger proportion among females with dependent personality disorders. Any diagnosis of personality disorder was a significant predictor of AD. Conclusions: Premorbid personality is poorly researched in populations with Alzheimers. It emerges as a predictor and it remains a significant presence in populations with AD particularly females in the dependant category. P2-124 SEX HORMONES AND TNF-ALPHA IN MEN WITH ALZHEIMER’S DISEASE Brian Birch, Joe Butchart, Laura Wolfe, Clive Holmes, University of Southampton School of Medicine, Southampton, United Kingdom.