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IC‐P‐126: Ultra‐high field 7‐tesla hippocampal imaging: A semi‐automated method for measuring stratal width
Author(s) -
Kerchner Geoffrey,
Dougherty Robert
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.091
Subject(s) - coronal plane , hippocampal formation , line (geometry) , perpendicular , hippocampus , stratum , atrophy , geology , nuclear medicine , physics , nuclear magnetic resonance , mathematics , computer science , geometry , anatomy , medicine , neuroscience , psychology , paleontology , pathology
comparison between converters and non-converters, we applied t-test. Statistical significance was defined as p < 0.05. Results: In a total of 56 cases, CM demonstrated slight distortions of the images in 16 cases and heavy distortions in 4 cases after anatomic standardization. NM did not show such distortions (Figure). Both methods demonstrated that the values for AD andMCI patients were significantly higher than those for NC at the parietal, temporal and occipital lobes. Only NM showed such significant differences at the frontal lobes. In addition, only NM demonstrated that converters showed significant higher values than non-converters at the parietal and frontal lobe. Conclusions: NM nicely modified anatomic standardization errors on 3D-SSP analyses for amyloid PET imaging. 3D-SSP analyses for BF227 imaging demonstrated significant differences between AD and NC, MCI and NC, and converters and non-converters.