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IC‐P‐119: Impaired connectivity between functional brain modules reflects cognitive dysfunction in Alzheimer's disease
Author(s) -
Haan Willem,
Flier Wiesje,
Koene Ted,
Smits Lieke,
Scheltens Philip,
Stam Cornelis
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.084
Subject(s) - magnetoencephalography , modularity (biology) , cognition , neuroscience , resting state fmri , psychology , disease , power graph analysis , functional connectivity , graph , audiology , medicine , electroencephalography , biology , computer science , genetics , theoretical computer science
was only moderate (0.46). Conclusions:With optimal minIP processing at 7T MRI, susceptibility artefacts of microbleeds from 0.7 mm in diameter or more were detected. However, the limited size of some of the lesions and susceptibility effects of adjacent other structures also complicated detection, reducing inter-rater reliability of visual scoring. Automated lesion detection techniques may be required to optimally benefit from the increased spatial resolution offered by 7T MRI.