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IC‐P‐035: Greater rate of atrophy in elderly with high versus low Aβ deposition
Author(s) -
Chételat Gaël,
Villemagne Victor,
Villain Nicolas,
Jones Gareth,
Ellis Kathryn,
Ames David,
Martins Ralph,
Head Richard,
Masters Colin,
Rowe Christopher
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.051
Subject(s) - pittsburgh compound b , atrophy , neocortex , magnetic resonance imaging , neurodegeneration , posterior cingulate , positron emission tomography , alzheimer's disease neuroimaging initiative , neuroimaging , psychology , pathological , neuroscience , alzheimer's disease , medicine , cardiology , cortex (anatomy) , pathology , disease , radiology
normalities than a voxel-wise analysis of either modality alone. Methods: Twenty-one patients with Mild Cognitive Impairment (MCI; 71 6 8 yrs, 11 women, MMSE 296 2) and 21 cognitively normal healthy elderly controls (CN; 706 7 yrs, 11 women, MMSE 296 1) were studied using voxelwise analysis. Images were registered to standard space, creating maps of deformation (JAC) and fractional anisotropy (FA). Group and age were in-
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