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P4‐145: Aspirin in Alzheimer's Disease: Increased Risk of Intracerebral Haemorrhage and no Clinical Benefit
Author(s) -
Richard Edo,
Thoonsen Hanneke,
Bentham Peter,
Gray Richard,
De Haan Rob J.,
Van Gool Willem A.,
Nederkoorn Paul J.
Publication year - 2010
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2010.08.204
Subject(s) - aspirin , medicine , dementia , vascular dementia , randomized controlled trial , stroke (engine) , disease , alzheimer's disease , relative risk , clinical trial , confidence interval , mechanical engineering , engineering
83.36 10 and 60.66 9.4 (p< 0.0001); Linguistic Comprehension: 98.76 5.3 and 91.16 6.6 (p1⁄4 0.0001), and Visuospatial Construction: 24.66 1.7 and 19.26 4.2 (p < 0.0001). Total score of ABCD was 83.26 4.8 for controls and 67.2 6 6.7 in the VaD group (p < 0.0001). Linguistic Expression tasks were more effective in discriminating VaD patients from controls than Linguistic Comprehension tasks. Conclusions: The ABCD is a useful tool to identify and discriminate linguistic performance of VaD patients from normal elderly. Executive dysfunction (including working memory), and attentional impairment, may have influenced the patients’ linguistic performance.