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P4‐034: Udp Attenuates Beta‐amyloid Burden and Reverses the Deficit of Long Term Potentiation in Psapp Animals
Author(s) -
Dong Jinghui,
Revilla-Sanchez Raquel,
Schmitt Luke,
Jackson Joshua,
Ellis-Davies Graham,
Pangalos Menelas,
Reinhart Peter,
Moss Stephen J.,
Haydon Philip G.
Publication year - 2010
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2010.08.094
Subject(s) - long term potentiation , microglia , hippocampus , in vivo , amyloid (mycology) , pathology , chemistry , cortex (anatomy) , amyloid beta , genetically modified mouse , medicine , endocrinology , inflammation , neuroscience , transgene , biology , receptor , disease , biochemistry , microbiology and biotechnology , gene
were found differences between MCIa group and Control group without depresión in intrusions at recall with clues (0.014), and at inmediat non related intrusions (0.045). There were not found significant differences at perseverations. Conclusions: Of the variables analized, the false positives represent the best differencial indicator between CD, Control group without depression and MCIa. Arises in the future to expand the sample to track which patients progress to AD and to determine the efficacy of these potential preclinical indicators.