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P3‐126: The usefulness of the Korean dementia screening questionnaire in patients with mild cognitive impairment and Alzheimer's disease
Author(s) -
Baek Min Jae,
Kim Hyun Jung,
Jang Il Mi,
Eah Kyung-Yoon
Publication year - 2010
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2010.05.1623
Subject(s) - dementia , cognitive impairment , disease , cognition , medicine , psychology , alzheimer's disease , activities of daily living , mini–mental state examination , gerontology , clinical psychology , psychiatry
Background: Dementia Screening Questionnaire is thought as a sensitive way to detect dementia patients and is not influenced by age and educational level. The Korean Dementia Screening Questionnaire (KDSQ) has recently been developed to screen among individuals with normal aging, mild cognitive impairment (MCI), and Alzheimer’s disease (AD) or other disorders causing dementia by asking an informant regarding elderly person’s everyday cognitive functions. The purpose of this study is to evaluate the usefulness of the KDSQ and its ability to discriminate between normal cognitive aging and patients with MCI or AD. Methods: The KDSQ was administered to informants of 456 patients (206 patients with MCI and 250 patients with AD) and 36 healthy elderly adults participated in this study. The three groups were matched in terms of age, gender, and education level. The KDSQ was compared with the Korean version of the Mini Mental State examination (KMMSE), and the instrumental activities of daily living (I-ADL), and validated Samsung dementia questionnaire (SDQ). Results: The KDSQ was not influenced by educational level, age, or gender. The area of under the curve for the KDSQ was 76% (S.E. 1⁄4 0.36). With respect to a diagnosis of dementia, the KDSQ (cut-off point 8) had a sensitivity of 81% and a specificity of 64%. Moreover, the KDSQ was well correlated with the K-MMSE (r1⁄4 -0.73), the I-ADL (r1⁄4 0.71), and the SDQ (r1⁄4 0.82). Conclusions: The KDSQ is a sensitive questionnaire for the diagnosis of patients with MCI or AD. It may be a useful tool for screening patients with MCI or AD.