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P3‐115: Cognitive activity and decline in Alzheimer's disease: The Cache County study
Author(s) -
Treiber Katherine,
Carlson Michelle,
Corcoran Chris,
Foley Beth,
Stein David M.,
Deberard Scott,
Maria Norton,
Piercy Kathleen,
Welsh-Bohmer Kathleen A.,
Breitner John C.S.,
Lyketsos Constantine,
Tschanz JoAnn T.
Publication year - 2010
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2010.05.1612
Subject(s) - cognitive reserve , clinical dementia rating , dementia , cognition , cognitive decline , psychology , gerontology , disease , neuropsychology , activities of daily living , medicine , clinical psychology , cognitive impairment , psychiatry
expert consensus panel. IADL limitations were obtained from interviews with informants for the participant. Results: Among individuals with dementia, a large number of participants did not complete the tests due to cognitive impairment or other reasons (e.g., 18.3% for Animal Fluency Test, 50.2% for Trail Making Test A, 77.6% for Trail Making Test B). Among those completing the test, significantly higher proportion of those with CIND and dementia had abnormal scores compared to those with normal cognition for each test (p < 0.001 for all tests). 18.4% of those with normal cognition, 57.0% of those with CIND and 89.1% of those with dementia had abnormal scores for at least one test. Among those with normal cognition or CIND, worse test scores were associated with a greater number of limitations in IADLs (p < 0.01 for all tests). Conclusions: Impairment on executive function measures may be common even among individuals without dementia, and it may be associated with IADL limitations. Assessing executive function for those without dementia may help to identify individuals with greater needs for daily support.