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P3‐019: Friendship and incidence of dementia: The monzino 80‐plus study
Author(s) -
Lucca Ugo,
Garrì Mariateresa,
Recchia Angela,
Riva Emma,
Nobili Alessandro,
Pasina Luca,
Franchi Carlotta,
Tettamanti Mauro
Publication year - 2010
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2010.05.1512
Subject(s) - dementia , friendship , incidence (geometry) , medicine , epidemiology , population , demography , gerontology , diabetes mellitus , psychology , disease , psychiatry , physics , social psychology , environmental health , sociology , optics , endocrinology
(70.6%) were women. MMSE scores were moderately and significantly correlated with transferrin saturation (r 1⁄4 0.32, p < 0.001). Transferrin saturation was significantly lower in the patients with dementia (25.7 (12.8-44.3) vs. 29.1 (3.7-49.8); p 1⁄4 0.040). ROC analysis revealed that the cut off 19.19 for transferrin saturation has an effect on dementia (sensitivity 40.7%, specificity 84.5%). Conclusions: The results of this study revealed that iron status may be related to cognitive dysfunction and dementia before reaching the severity to cause anemia. Different cut off values of transferrin saturation, varying from 15 to 18, have been given in the literature for iron deficiency. This study shows that 19.19 can be an appropriate cut off value.