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P2‐360: Severe MRI hippocampal atrophy distinguishes hippocampal sclerosis from Alzheimer's disease and other neuropathologic disorders
Author(s) -
Zarow Chris,
Zheng Ling,
Chui Helena C.,
White Lon R.
Publication year - 2010
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2010.05.1412
Subject(s) - subiculum , hippocampal formation , atrophy , receiver operating characteristic , hippocampal sclerosis , hippocampus , medicine , alzheimer's disease , entorhinal cortex , dementia , neuroscience , psychology , pathology , temporal lobe , epilepsy , disease , dentate gyrus
ERC. In aMCI studies, ERC volume loss appears more important that HC volume loss. The variability of measurements between aMCI and LLD studies raises the important issue of comparability. Future volumetric studies could benefit from using standardized segmentation protocols. No volumetric studies focusing on aMCI subjects with concomitant depression were found, and hence are needed in order to validate our interpretations.