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P2‐353: MR microimaging detects subfield‐specific neuronal loss in the hippocampus
Author(s) -
Venkatasubramanian Palamadai N.,
Banks Benjamin,
Iordanescu George,
Pych Jason C.,
Wyrwicz Alice M.
Publication year - 2010
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2010.05.1405
Subject(s) - hippocampus , genetically modified mouse , pyramidal cell , neuroscience , transgene , wild type , entorhinal cortex , hippocampal formation , biology , pathology , medicine , biochemistry , mutant , gene
overlapping imaging windows. Results: The analysis model proposed above resulted in approximately 66% of the standard error of the estimates compared to the simplified model. There was no substantial change in the magnitude of the estimates. Due to the smaller standard error, precise estimates for the comparison of the two VOI boundary strategies for cortical VOI could be established. Conclusions: The additional data included in the proposed analysis model is highly correlated with the data from the non-overlapping imaging windows. Nevertheless, we could show, that the proposed analysis model results in an evident decrease in the length of the confidence interval of about 33%, compared to the simplified model.