P2‐065: Burden interview versus neuropsychiatric inventory: Evaluation of burden in caregivers of Alzheimer's disease patients

This study aims to evaluate patient and caregiver’s characteristics related with neuropsychiatric symptoms. Methods: A cross-sectional study was conducted in a sample of 58 probable Alzheimer’s disease (AD) patients (NINCDS-ADRDA criteria). The neuropsychiatric symptoms were evaluated by the Brazilian version of the Neuropsychiatric Inventory (NPI). The dementia severity was assessed with the Clinical Dementia Rating (CDR), Brazilian version. The analyzed patient’s variables were sex, age, age of onset of AD symptoms and education. The analyzed caregiver’s variables were sex, type of relationship, age, education, time as caregiver, weekly time of care, residing with patient and type of job. Student’s t test and one-way Anova were performed for parametric variables. Spearman’s rho was used for correlations. Results: NPI intensity and distress were similar in both patient’s sex (p 1⁄4 0.742 and p 1⁄4 0.902, respectively) and in the three stages of severity of dementia (F1⁄4 1.951, p1⁄4 0.152; F1⁄4 0.763, p1⁄4 0.471, respectively). Patient’s education was inversely correlated with NPI frequency, intensity and distress (rho1⁄4 -0.283, rho1⁄4 -0.276, rho1⁄4 -0.262, p1⁄4 0.05). NPI intensity and distress were similar in both caregiver’s sex (p1⁄4 0.809 and p1⁄4 0.743, respectively), relationship type (p> 0.5) and caregiver’s type of job (p > 0.5). However, a tendency for statistical difference was observed between caregivers who resided and those who not resided with patients (p 1⁄4 0.05), caregivers who resided with patients showed higher NPI intensity and NPI distress. Caregiver’s education was inversely correlated with NPI frequency, intensity and distress (rho1⁄4 -0.302, rho1⁄4 -0. 272, rho1⁄4 -0. 300, p1⁄4 0.05). Caregiver’s age was inversely correlated with NPI severity (rho 1⁄4 -0.270, p 1⁄4 0.05). Weekly time of care was correlated with NPI frequency (rho 1⁄4 0. 291, p1⁄4 0.05). Conclusions: Some variables may interfere on neuropsychiatric symptoms evaluation by caregivers of AD patients, as age, education, weekly time of care and residing with patients. Some of them can be modified through different approaches improving quality of care.