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P2‐041: Economic costs of dementia in Argentina: A comparison between vascular, frontotemporal and Alzheimer's dementia
Author(s) -
Rojas Galeno J.,
Bartoloni Leonardo,
Dillon Carol,
Serrano Cecilia,
Allegri Ricardo F.
Publication year - 2010
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2010.05.1061
Subject(s) - dementia , vascular dementia , frontotemporal dementia , medical prescription , medicine , disease , gerontology , alzheimer's disease , health care , cohort , psychiatry , political science , law , pharmacology
of daily living (ADL) and caregiver’s burden by Zarit Inventory (ZI). The effect of behavior on direct costs of care was examined. Results: For all subtypes of dementia the incremental cost of a one-point increase in BDI was $44 per trimester. Nevertheless total NPI score didn’t show a significant increase of direct costs. There was a significant independent relationship between direct costs and caregiver’s burden, activities of daily life, depression and education (r2 1⁄4 0.76). Sensitivity analysis using log-transformed costs did not change these results. In Alzheimer’s disease the incremental cost of a one-point increase in activities of daily living was $62 per trimester. For frontotemporal dementia variables leading to increased costs were lower MMSE, greater age and higher BDI (p< 0.05). There weren’t significant independent variables for vascular dementias. Conclusions: Depression contributes significantly to the direct costs of dementia, particularly for frontotemporal dementia. The relationship between cognitive variables and costs are not the same in the different subtypes of dementia. Interventions targeted at BPSD may help to reduce the social costs of illness.