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IC‐P‐029: Differential diagnosis of neurodegenerative dementias using structural MRI
Author(s) -
Vemuri Prashanthi,
Kantarci Kejal,
Senjem Matthew L.,
Gunter Jeffrey L.,
Whitwell Jennifer L.,
Josephs Keith A.,
Knopman David S.,
Boeve Bradley F.,
Ferman Tanis J.,
Dickson Dennis W.,
Petersen Ronald C.,
Jack Clifford R.
Publication year - 2009
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2009.05.049
Subject(s) - dementia , differential diagnosis , frontotemporal lobar degeneration , atrophy , dementia with lewy bodies , pathology , frontotemporal dementia , lewy body , pathological , neurology , medicine , disease , abnormality , psychology , neuroscience , psychiatry
CONCLUSIONS: STAND-Map of each dementia syndrome in pathologically confirmed cases is unique and may be very useful for the differential diagnosis of new incoming subjects. The proposed framework establishes a direct relationship between a structural abnormality biomarker (MRI) and the “gold standard” of pathology. This information is then incorporated to provide differential diagnosis in new incoming patients with dementia. This system can also be used to determine the relative contribution of several different disease processes underlying the clinical presentation of dementia in an individual subject.