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P3‐293: Investigation of the critical amino acids in the BACE1 binding site that interact with small molecule inhibitors using a novel radioligand and X‐ray crystallography
Author(s) -
Hirst Warren D.,
Kubek Katie,
Bard Jonathan,
Turner James,
Fan Kristi,
Malamas Michael,
Reinhart Peter H.,
Robichaud Albert J.
Publication year - 2009
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2009.04.964
Subject(s) - ectodomain , radioligand , chemistry , binding site , cleavage (geology) , enzyme , stereochemistry , protease , amyloid precursor protein , biochemistry , proteases , small molecule , biology , receptor , alzheimer's disease , medicine , paleontology , disease , pathology , fracture (geology)