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P3‐291: Putative gamma secretase modulators lower Aβ 42 in multiple in vitro and in vivo models
Author(s) -
Rogers Kathryn,
Chesworth Richard,
Felsenstein Kevin,
Shapiro Gideon,
Albayya Faris,
Tu Zhiming,
Spaulding Darcie,
Catana Florentina,
Hrdlicka Lori,
Nolan Scott,
Wen Melody,
Yang Zhiyong,
Vulsteke Veerle,
Patzke Holger,
Koenig Gerhard,
DeStrooper Bart,
Ahlijanian Michael
Publication year - 2009
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2009.04.962
Subject(s) - gamma secretase , in vitro , in vivo , ic50 , western blot , chemistry , notch signaling pathway , cell culture , pharmacology , cytotoxicity , microbiology and biotechnology , biochemistry , biology , signal transduction , gene , genetics