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P4‐067: Differences of neuropsychological function and behavioral symptoms between depressive elderly patients with or without subjective memory complaint
Author(s) -
Kim MoonDoo,
Lee ChangIn,
Hong SeongChul
Publication year - 2009
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2009.04.836
Subject(s) - activities of daily living , dementia , depression (economics) , geriatric depression scale , recall , psychology , verbal fluency test , complaint , cognition , clinical dementia rating , clinical psychology , neuropsychology , logistic regression , psychiatry , depressive symptoms , medicine , cognitive impairment , disease , political science , law , economics , cognitive psychology , macroeconomics
loss should reveal limbic system dysfunction and loss of valence association to cognitive information. Methods: To counterpart the miss of test sensitivity and to bring to light this early symptom, we proposed: (1) to evaluate separately inhibition and then inhibition-emotion efficiencies in comparing 10 early AD (MMSE 1⁄4 21-26, mean age 1⁄4 80), 10 old (mean age 1⁄4 79) and 10 young adults (mean age 1⁄4 23) on Standard and Emotional Stroop (emotion perception), (2) to control the incidence of individual efficiency on cognition, using the NEPSY neuropsychological test (Korkman et al., 1998), on emotion with the Multiple Emotional Intelligence Scale (Mayer & Salovey, 1997) on depression-apathy and socio-educational level. If affect loss severely diminishes somatic marking of cognitive information, AD capacity of inhibition will not be affected by emotional valence associated to information. Results: The initial results indicate a relative increase of errors number between Standard et Emotional Stroop from AD patients to young adults but no reaction time differences. Conversely, emotional sensibility differs between young adults and AD patients, depending on emotion perception, understanding and regulation. Executive functions vary at intergroup and intragroup levels. Individual results are, actually, explored in function of these three indicators and will be presented, as influence of positive and negative valence. Conclusions: More generally, if AD cognitive-emotional damage can be easily demonstrated, the degree of validity of early diagnostic of AD will increase, treatments will begin earlier and capacity to report enter in severe phase of AD will increase, too. This progress could benefit to patients, caregivers and Public Health.