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P2‐089: Prevalence and illnesses causing early‐onset dementia in Japan: A multi‐center study
Author(s) -
Ikejima Chiaki,
Ikeda Manabu,
Hashimoto Mamoru,
Ogawa Yusuke,
Tanimukai Satoshi,
Kashibayashi Tetsuo,
Miyanaga Kazuo,
Yonemura Kimie,
Kakuma Tatsuyuki,
Asada Takashi
Publication year - 2009
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2009.04.399
Subject(s) - dementia , dementia with lewy bodies , vascular dementia , medicine , population , disease , gerontology , pediatrics , epidemiology , prevalence , demography , environmental health , pathology , sociology
aim of this study is to evaluate the frequency of cognitive deficit and depressive symptoms in patients stratified according to the risk of developing cardiovascular events, as well as to compare the cognitive performance between low and high risk groups. Methods: The Framingham Score was used to stratify 110 patients in low, medium or high risk for cardiovascular disease. The Mini Mental State Examination (MMSE) and the Geriatric Depression Scale (GDS-15) were used to evaluate the cognitive performance and the presence of depressive symptoms. The cutoff for the presence of depressive symptoms was considered 6 on GDS. Results: The high risk group showed significant lower scores on MMSE (p<0.001) regardless of education when compared to the other groups. The GDS-15 results did not differ significantly among the groups of cardiovascular risk (p1⁄40.161) however, they showed that the prevalence of depressive symptoms was higher (37%) in the group with cardiovascular risk than in the general population (5-17%). Conclusions: The present findings corroborate the differential cognitive performance of patients with high cardiovascular risk. It was also noted the high prevalence of depressive symptoms in patients with cardiovascular risk, although it was not significantly different among the groups, it was higher than in the general population.