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P2‐066: Web‐based application to estimate and project the burden of Alzheimer's disease and evaluate the impact of potential interventions
Author(s) -
Colantuoni Elizabeth,
Hackman Andre,
Brookmeyer Ron,
Arrighi H. Michael
Publication year - 2009
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2009.04.376
Subject(s) - psychological intervention , disease , population , medicine , quality adjusted life year , disease burden , burden of disease , public health , population ageing , gerontology , intervention (counseling) , environmental health , health care , incidence (geometry) , cost effectiveness , risk analysis (engineering) , nursing , physics , pathology , optics , economics , economic growth
compared to AD group: 115.3632.1vs 88.9613.2 mg/dL (p<0.0001), and controls 90.2612.4 mg/dL (p<0.0001). No difference was recorded in mean TG or FPG between AD patients and controls. When classified by decennial age strata, a same pattern of results was recorded for all subgroups. Across dementia staging by CDR, mean cholesterol, triglycerides, and glucose levels were significantly higher in VaD compared to AD group across all CDR subgroups. Differences persisted when VaD patients were classified by disease duration subgroups. Conclusions: These results suggest that there are substantial differences in the studied biochemical parameters, which may prove valuable in helping to distinguish appreciatively subjects with AD from those with VaD, at any time point of the disease course, i.e. mild vs frank hypercholesterolemia, normal vs normal or higher triglyceridemia, normal vs normal or higher glycemia, in AD vs VaD respectively.