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P1‐174: Stability and prediction of future dementia for multiple transitional cognitive states: The cache county study
Author(s) -
Warren Lauren Half,
Hayden Kathleen M.,
Sanders Linda,
Ostbye Truls,
Pieper Carl F.,
Tschanz JoAnn T.,
Norton Maria C.,
Hartman Marilyn,
Welsh-Bohmer Kathleen A.
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.762
Subject(s) - dementia , neuropsychology , cognition , logistic regression , cognitive decline , psychology , cognitive impairment , gerontology , medicine , psychiatry , disease
and above is estimated to be roughly 150 billion dollars by 2007 in the United States. Consistent predictors for nursing home admission include increased age, living alone, female gender, behavioural disturbances, decreased activity of daily living (ADL), and cognitive impairment. Subjective memory complaints are common among elderly persons; however, it is not known whether subjective memory complaints may be associated with an elevated risk of nursing home admission. Thus, the aim of this present study was to investigate whether subjective memory complaints in an elderly primary care population was associated with an elevated risk of nursing home admission during a four-year follow-up period. Methods: Prospective primary care cohort survey with a four-year follow-up. At baseline 758 non-nursing home residents aged 65 years and older consulting their General Practitioner in October and November 2002 were recruited. Cox proportional hazard models were used to examine the influence of risk factors on nursing home placement. Results: A total of 50 nursing home admissions were observed. Subjective memory complaints were associated with an adjusted Hazard Ratio (HR) of 2.6 for nursing home admission. Other statistical significant covariates were MMSE 24 (HR 5.28), Age (HR 4.56 for 75-84 years and HR 23.90 for 85 years) and extreme anxiety/depression (HR 5.26). The effect of subjective memory complaints seemed to be lower for subjects who were older at baseline. Conclusions: A total of 50 nursing home admissions were observed. Subjective memory complaints were associated with an adjusted Hazard Ratio (HR) of 2.6 for nursing home admission. Other statistical significant covariates were MMSE 24 (HR 5.28), Age (HR 4.56 for 75-84 years and HR 23.90 for 85 years) and extreme anxiety/depression (HR 5.26). The effect of subjective memory complaints seemed to be lower for subjects who were older at baseline.