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P1‐079: Calpain inhibition by calpastatin overexpression reduces β‐amyloid deposition in an APP transgenic mouse
Author(s) -
Morales-Corraliza Jose,
Berger Jason D.,
Mazzella Matthew J.,
Staufenbiel Matthias,
Rao Mala V.,
Nixon Ralph A.,
Mathews Paul M.
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.665
Subject(s) - calpastatin , calpain , genetically modified mouse , transgene , amyloid precursor protein , endogeny , microbiology and biotechnology , proteases , chemistry , senile plaques , biology , endocrinology , medicine , biochemistry , alzheimer's disease , enzyme , gene , disease