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P1‐038: Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease
Author(s) -
Marcello Andrea,
Breyhan Henning,
Bayer Thomas A.,
Wirths Oliver
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.623
Subject(s) - neurodegeneration , astrocyte , neuroinflammation , pathology , synaptophysin , spinal cord , western blot , gliosis , immunohistochemistry , glial fibrillary acidic protein , neuroscience , microglia , astrogliosis , genetically modified mouse , cathepsin d , hippocampal formation , medicine , biology , inflammation , central nervous system , disease , transgene , immunology , biochemistry , gene , enzyme