Premium
O4‐03–04: Mutational analysis of the GxGD‐protease active‐site domain of presenilin 1 reveals structural requirements for γ‐secretase substrate binding and cleavage
Author(s) -
Steiner Harald,
Pérez-Revuelta Blanca I.,
Kretner Benedikt,
Yamasaki Aya,
Lammich Sven,
Haass Christian
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.521
Subject(s) - presenilin , active site , nicastrin , mutant , biochemistry , protein subunit , chemistry , protease , docking (animal) , binding site , cleavage (geology) , enzyme , microbiology and biotechnology , stereochemistry , biology , gene , alzheimer's disease , medicine , paleontology , nursing , disease , pathology , fracture (geology)