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O4‐03–03: C‐terminal PAL motif of presenilin 1 comprises the subsite of gamma‐secretase within the catalytic pore
Author(s) -
Tomita Taisuke,
Sato Chihiro,
Takagi Shizuka,
Iwatsubo Takeshi
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.520
Subject(s) - presenilin , chemistry , transmembrane domain , transmembrane protein , membrane , stereochemistry , cytoplasm , c terminus , gamma secretase , biochemistry , mutant , biophysics , amino acid , receptor , biology , pathology , gene , alzheimer's disease , medicine , disease