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P4‐091: Profile epidemiologic of the advanced in years attends by Alzheimer Project‐APOE: Preliminary results
Author(s) -
Moreira Elza Maria,
Jacomini Anielle,
Galera Bianca Borsatto,
Cordeiro Bruna Grassiela,
Oliveira Amaral Camilla Magalhães
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.2156
Subject(s) - apolipoprotein e , epidemiology , disease , residence , gerontology , demography , allele , medicine , psychology , genetics , biology , gene , sociology
those mentioned, plus midlife BMI; midlife total cholesterol; lifetime smoking; diabetes, late life blood glucose and insulin; fibrinogen; head size; and history of head injury. Conclusions: Our findings emphasize the uncertainties involved in the interpretation of data linking risk factor exposures to clinical endpoints in late life, and the challenges implicit in assessment of interventions directed at specific pathogenic processes involved in cognitive decline and dementia in late life.