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P4‐071: Midlife coffee and tea drinking and later dementia: A population‐based Cardiovascular Risk Factors, Aging and Dementia (CAIDE) study
Author(s) -
Eskelinen Marjo H.,
Ngandu Tiia,
Tuomilehto Jaakko,
Soininen Hilkka,
Kivipelto Miia
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.2136
Subject(s) - dementia , medicine , logistic regression , gerontology , population , caffeine , disease , environmental health , demography , psychiatry , sociology
ities, diabetes and dyslipidemia were present in 24.8% and 29.7% of patients, respectively. Vascular risk factors, hypertension and smoking, were present in 48.6% and 10.8% of patients; heart disease, 13.5% and stroke, 8.1%, of patients. MRI findings showed the presence white matter changes in 60% and 12% with old infarcts. Diffuse cerebral atrophy was also in 83.3% of patients and 13.3% had hippocampal atrophy. Conclusions: Metabolic and vascular abnormalities are frequent co-morbidities in AD. In addition to specifically treating dementia symptoms in AD, clinical care for individuals with AD must equally tackle these conditions as it may contribute to reduce the rate of cognitive decline.