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P3‐442: Comparison of costs of care between patients with Alzheimer's disease and dementia with Lewy bodies
Author(s) -
Zhu Carolyn,
Scarmeas Nikolaos,
Albert Marilyn,
Brandt Jason,
Blacker Deborah,
Sano Mary,
Stern Yaakov
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.2012
Subject(s) - dementia with lewy bodies , dementia , medicine , disease , indirect costs , severe dementia , psychiatry , gerontology , pediatrics , accounting , business
stig-Kungsholmen project, based on the RUD (Resource Utilization in Dementia) instrument. The transition probabilities for CDR 1-3 were derived from the Kungsholmen project. Several simulations and cost profiles as well as a comprehensive sensitivity analysis were accomplished. The viewpoint was societal and the discount rate was 3%. Results: The underlying annual costs of CDR-states 1,2 and 3 were 14,308 US$, 25,872 US$, and 35,085 US$ respectively. After 3 years, the simulated cohort was reduced by 50% and after 10 years 97% was estimated to be dead with a mean survival time of 3.9 years. The total costs during the whole simulated period was 2.3 billions US$ (for CDR states 1,2 and 3 0.65, 0.60 and 1.07 billions US$ respectively). The institutional cost proportion was 58%, 75% and 84% respectively and it was 62% in year 1 and 81% in year 10. With an increase in the informal care hourly cost from 13 to US$ 31 and with supervision time included, the costs increased from 2.3 to 4.0 billions US$. A reduction of annual mortality in CDR1 from 12 to 8% and in CDR3 from 48 to 30% increased costs from 2.3 to 2.5 and 2.7 billions US$ respectively. Conclusions: The highest costs occur in CDR3. However, the costs of CDR1 are on the same level as CDR2, even if the state specific cost in CDR1 is much lower. Costs are sensitive for assumptions regarding informal care and mortality.