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P3‐373: Amyloid plaque‐associated activated microglia are primed for the expression of IDO and production of exitotoxin quinolinic acid in response to systemic lipopolysaccharide‐induced brain inflammatory stimuli in a Tg2576 mouse model of Alzheimer's disease
Author(s) -
Takikawa Osamu,
Akikmoto Hidetoshi,
Kagawa Syota,
Yamada Akiko,
Guillemin Gilles J.
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.1943
Subject(s) - quinolinic acid , microglia , kynurenine pathway , indoleamine 2,3 dioxygenase , kynurenine , lipopolysaccharide , hippocampus , amyloid (mycology) , chemistry , medicine , endocrinology , immunology , inflammation , tryptophan , biochemistry , pathology , amino acid