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P2‐482: De novo design of cellular active beta‐secretase inhibitors
Author(s) -
Mok Ngai Y.,
Chadwick James,
Davey Katherine A.B.,
Hooper Nigel M.,
Johnson A. Peter,
Fishwick Colin W.G.
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.1560
Subject(s) - peptide , enzyme , amyloid precursor protein , amyloid beta , chemistry , drug discovery , rational design , in vitro , active site , amyloid (mycology) , amyloid precursor protein secretase , small molecule , high throughput screening , mutant , biochemistry , gamma secretase , ic50 , alzheimer's disease , nanotechnology , gene , medicine , materials science , inorganic chemistry , disease , pathology