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P2‐421: A multinutrient intervention but not omega‐3 PUFA‐rich fish oil by itself reduces depression relevant to Alzheimer's disease
Author(s) -
Broersen Laus M.,
Wilde Martijn C.,
Balvers Martin,
Olivier Berend,
Kamphuis Patrick J.
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.1500
Subject(s) - depression (economics) , fish oil , polyunsaturated fatty acid , disease , medicine , neuroprotection , physiology , antidepressant , psychiatry , biology , anxiety , fish <actinopterygii> , biochemistry , fatty acid , macroeconomics , fishery , economics
depression in both groups (Group 1: 18.72 9.10, Group 2: 19.95 7.86). Performance for words was highest in both groups (Group 1: 89 12, Group 2: 79 22) and accompanied by lowest error scores (0.06.and 0.13, respectfully). The worst performance was found to be in textures (62 24 and 65 23). Mean reaction time ranged from 1039 ms to 1504 ms. Reaction time was shortest when textures were presented (Group 1: 1039 ms, Group 2: 1199 ms) and longest when numbers were presented (1503 ms, 1504 ms). Based on performance profile for different stimuli, individual memory training protocols were designed, with an emphasis on numbers and words, which were the stimuli with the highest performances in this particular group. Conclusions: We have demonstrated the feasibility of using N-back task for prompt assessment of working memory profile in people with dementia and depression. We believe that the results of this paradigm are useful for the development of individual memory training protocols.