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IC‐P3‐161: Longitudinal study of change of atrophy and cognition in African‐Americans and Caucasians in a community population
Author(s) -
Aggarwal Neelum,
Bienias Julia L.,
Wilson Robert S.,
Bennett David A.,
Persianinova Maria,
Kim Jane,
Tran Jeannie,
Zozulya Nataliya,
Fletcher Evan,
Evans Denis A.,
DeCarli Charles
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.105
Subject(s) - atrophy , brain size , cognitive decline , dementia , population , gerontology , medicine , longitudinal study , cognition , psychology , demography , disease , magnetic resonance imaging , pathology , psychiatry , environmental health , sociology , radiology
component correlated with FA. Conclusions: The positive correlation between hippocampal FA and dendrites supports the hypothesis that barriers to diffusion created by hippocampal dendrites account for differences observed in FA. Further, the present results suggest that the Tg2576 mice in [1] failed to add dendrites between 3 and 5 months of age. Future experiments will utilize DTI to investigate the relationship between hippocampal dendrites and other aspects of AD pathology with the ultimate goal of integrating DTI of the hippocampus into clinical diagnosis of AD.