Premium
IC‐P1‐003: Registration of serial MRI improves diagnosis of dementia
Author(s) -
Barnes Josephine,
Mitchell L. Anne,
Kennedy Jonathan,
Barker Suzie,
Lehmann Manja,
Nordstrom R. Christopher,
Frost Chris,
Smith Joseph R.,
Garde Ellen,
Rossor Martin N.,
Fox Nick C.
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.016
Subject(s) - medicine , dementia , pathological , atrophy , cognitive impairment , test (biology) , radiology , disease , pediatrics , pathology , paleontology , biology
(p 0.04) inferior parietal, right (p 0.004) and left (p 0.01) superior parietal and left temporal pole (p 0.01). Comparing AD to aMCI, we also found a similar pattern of atrophic brain areas: right (p 0.0005) and left (p 0.007) thalamus, right (0.008) and left hippocampus (p 0.006), right (p 0.001) and left (p 0.01) caudate nucleus, right (p 0.01) and left (p 0.03) opercular part of inferior frontal gyri, right insula (p 0.03), right (p 0.02) and left (p 0.002) inferior parietal gyri and left temporal pole (p 0.02). Conclusions: We found several atrophic brain areas in mild AD patients in comparison to aMCI and normal controls, the most significative on temporal medial structures and bilateral thalamus. IC-P1-003 REGISTRATION OF SERIAL MRI IMPROVES DIAGNOSIS OF DEMENTIA